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Arun Karlamangla

Arun Karlamangla

Professor of Medicine, Department of Geriatrics
University of California-Los Angeles
akarlamangla@mednet.ucla.edu
http://www.geronet.med.ucla.edu/research/researchers/377?831a6a7603aca2da33e5c8f97a3f7b84=947d93b178bb37f1b3e63e6371ec6038


Arun Karlamangla, PhD, MD, is a geriatrician and clinical epidemiologist at the University of California, Los Angeles. His primary research interests are in the epidemiology of age-related diseases and functional decline, prediction of disease risks in older adults, and the physiological pathways by which psychosocial stressors affect health outcomes. Ongoing research studies focus on the development and validation of a cardiovascular risk score tailored to older adults, determination of trajectories of change in integrated measures of bone strength in women going through the menopause, delineation of physiological pathways by psychosocial life histories affect bone strength in midlife. He also serves as statistical consultant on national studies, and co-directs the analysis core of MIDUS, and the analys and cost effectiveness core of UCLA's Older Americans Independence Center.



Representative Publications
Galen Buckwalter, J., Castellani, B., McEwen, B., Karlamangla, A. S., Rizzo, A. A., John, B., O'Donnell, K., & Seeman, T. (2016). Allostatic load as a complex clinical construct: A case-based computational modeling approach. Complexity, 21(S1), 291-306.
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Wiley, J. F., Gruenewald, T. L., Karlamangla, A. S., & Seeman, T. E. (2016). Modeling multisystem physiological dysregulation. Psychosomatic Medicine, 78(3), 290-301.
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Tsenkova, V. K., Karlamangla, A. S., & Ryff, C. D. (2016). Parental history of diabetes, positive affect, and diabetes risk in adults: Findings from MIDUS. Annals of Behavioral Medicine, 50(6), 836-843.
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Tsenkova, V. K., & Karlamangla, A. (2016). Depression amplifies the influence of central obesity on 10-year incidence of diabetes: Findings from MIDUS. PLoS ONE, 11(10), e0164802.
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Crandall, C. J., Karlamangla, A. S., Merkin, S. S., Binkley, N., Carr, D., Greendale, G. A., & Seeman, T. E. (2015). Adult bone strength of children from single-parent families: The Midlife in the U.S. Study. Osteoporosis International, 26(3), 931-942.
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Friedman, E. M., Karlamangla, A. S., Gruenewald, T., & Seeman, T. E. (2015). Early life adversity and adult biological risk profiles Psychosomatic Medicine, 77(2), 176-185.
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Brooks, K. P., Gruenewald, T. L., Karlamangla, A., Hu, P., Koretz, B., & Seeman, T. E. (2014). Social relationships and allostatic load in the MIDUS Study. Health Psychology, 33(11), 1373-1381.
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Karlamangla, A. S., Miller-Martinez, D., Lachman, M. E., Tun, P. A., Koretz, A., & Seeman, T. M. (2014). Biological correlates of adult cognition: Midlife in the United States (MIDUS). Neurobiology of Aging, 35(2), 387-394.
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Srikanthan, P., Crandall, C. J., Miller-Martinez, D., Seeman, T. E., Greendale, G. A., Binkley, N., & Karlamangla, A. S. (2014). Insulin resistance and bone strength. Findings from the study of Midlife in the United States. Journal of Bone and Mineral Research, 9(4), 796-803.
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Miller-Martinez, D., Seeman, T., Karlamangla, A. S., Greendale, G. A., Binkley, N., & Crandall, C. J. (2014). Marital histories, marital support, and bone density: Findings from the Midlife in the United States study. Osteoporosis International, 25(4), 1327-1335.
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Mori, T., Karlamangla, A. S., Merkin, S. S., Crandall, C. J., Binkley, N., Greendale, G. A., & Seeman, T. E. (2014). Multi-system dysregulation and bone strength: Finding from the Study of Midlife in the United States. Journal of Clinical Endocrinology and Metabolism, 99(5), 1843-1851.
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Seeman, M., Stein Merkin, S., Karlamangla, A., Koretz, B., & Seeman, T. (2014). Social status and biological dysregulation: The "status syndrome" and allostatic load. Social Science & Medicine, 118, 143-151.
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Tsenkova, V., Pudrovska, T., & Karlamangla, A. (2014). Childhood socioeconomic disadvantage and prediabetes and diabetes in later life: A study of biopsychosocial pathways. Psychosomatic Medicine, 76(8), 622-628.
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Karlamangla, A. S., Mori, T., Merkin, S. S., Seeman, T. E., Greendale, G. A., Binkley, N., & Crandall, C. J. (2013). Childhood socioeconomic status and adult femoral neck bone strength: Findings from the Midlife in the United States Study. Bone, 56(2), 320-326.
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Karlamangla, A. S., Friedman, E. M., Seeman, T. E., Stawksi, R. S., & Almeida, D. M. (2013). Daytime trajectories of cortisol: Demographic and socioeconomic differences- findings from the National Study of Daily Experiences. Psychoneuroendocrinology, 38, 2585-2597.
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Crandall, C. J., Miller-Martinez, D., Greendale, G. A., Binkley, N., Seeman, T. E., & Karlamangla, A. S. (2012). Socioeconomic status, race, and bone turnover in the Midlife in the U.S. Study. Osteoporosis International, 23(5), 1503-1512.
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Turiano, N. A., Pitzer, L., Armour, C., Karlamangla, A., Ryff, C. D., & Mroczek, D. K. (2012). Personality trait level and change as predictors of health outcomes: Findings from a national study of Americans (MIDUS). The Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 67(1), 4-12.
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Gruenewald, T. L., Karlamangla, A. S., Hu, P., Stein-Merkin, S., Crandall, C., Koretz, B., & Seeman, T. E. (2012). History of socioeconomic disadvantage and allostatic load in later life. Social Science and Medicine, 74(1), 75-83.
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Friedman, E. M., Karlamangla, A. S., Almeida, D. M., & Seeman, T. E. (2012). Social strain and cortisol regulation in Midlife in the US. Social Science & Medicine, 74(4), 607-615.
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Crandall, C. J., Merkin, S. S., Seeman, T. E., Greendale, G. A., Binkley, N., & Karlamangla, A. S. (2012). Socioeconomic status over the life-course and adult bone mineral density: The Midlife in the U.S. Study. Bone, 51(1), 107-113.
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Taylor, S. E., Karlamangla, A. S., Friedman, E. M., & Seeman, T. E. (2011). Early environment affects neuroendocrine regulation in adulthood. Social Cognitive and Affective Neuroscience, 6(2), 244-251.
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Seeman, T. E., Miller-Martinez, D. M., Stein Merkin, S., Lachman, M. E., Tun, P. A., & Karlamangla, A. S. (2011). Histories of social engagement and adult cognition: Midlife in the US study. Journals of Gerontology. Series B, Psychological Sciences and Social Sciences, 66B(Suppl 1), i141-i152.
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Miller, G. E., Lachman, M. E., Chen, E., Gruenewald, T. L., Karlamangla, A. S., & Seeman, T. E. (2011). Pathways to resilience: Maternal nurturance as a buffer against the Effects of childhood poverty on metabolic syndrome at Midlife. Psychological Science, 22(12), 1591-1599.
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Greendale, G.A., SafaeiNili, N., Huang, M.-H., Seeger, L., & Karlamangla, A.S. (2010). The reliability and validity of three non-radiological measures of thoracic kyphosis and their relations to the standing radiological Cobb angle. Osteoporosis International. Advanced online publication.

Chodosh, J., Miller-Martinez, D., Aneshensel, C.A., Wight, R.G., & Karlamangla, A.S. (2010). Depressive symptoms, chronic diseases, and physical disabilities as predictors of cognitive functioning trajectories in older Americans. Journal of the American Geriatrics Society, 58(12), 2350-2357.

Greendale, G.A., Wight, R.G., Huang, M.H., Avis, N., Gold, E., Joffe, H., Seeman, T., Vuge, M., & Karlamangla, A.S. (2010). Menopause-associated symptoms and cognitive performance: Results from the Study of Women's Health Across the Nation. American Journal of Epidemiology, 171(11), 1214-1224.

Karlamangla, A.S., Merkin, S.S., Crimmins, E.M., & Seeman, T.E. (2010). Socioeconomic and ethnic disparities in cardiovascular risk in the United States, 2001-2006. Annals of Epidemiology, 20, 617-628.

Srikanthan, P., Hevener, A.L., & Karlamangla, A.S. (2010). Sarcopenia exacerbates obesity-associated insulin resistance and dysglycemia: Findings from the National Health and Nutrition Examination Survey III. PLoS ONE, 5(5), e10805.

Seeman, T.E., Merkin, S.S., Crimmins, E.M., & Karlamangla, A.S. (2010). Disability trends among older americans: National Health and Nutrition Examination Surveys, 1988-1994 and 1999-2004. American Journal of Public Health, 100(1), 100-107.

Seeman, T., Gruenewald,T., Karlamangla, A., Sidney, S., Liu, K., McEwen, B., & Schwartz, J. (2010). Modeling multisystem biological risk in young adults: The Coronary Artery Risk Development in Young Adults Study. American Journal of Human Biology, 22(4), 463-472.

Karlamangla, A.S., Miller-Martinez, D., Aneshensel, C.S., Wight, R.G., Seeman, T.E., & Chodosh, J. (2009). Trajectories of cognitive function in late life in the United States: Demographic and socioeconomic predictors. American Journal of Epidemiology, 170(3), 331-342.

Srikanthan, P., Seeman, T.E., & Karlamangla, A.S. (2009). Waist-hip ratio as a predictor of all-cause mortality in high-functioning older adults. Annals of Epidemiology, 19(10), 724-731.

Greendale, G.A., Huang, M.H., Wight, R.G., Seeman, T.E., Luetters, C., Avis, N.E., Johnston, J, & Karlamangla, A.S. (2009). Effects of the menopause transition and hormone use on cognitive performance in mid-life women: Results from the Study of Women's Health Across the Nation (SWAN). Neurology, 72, 1850-1857.

Karlamangla, A.S., Sarkisian, C., Kado, D., Dedes, H., Liao, D.H., Kim, S., Reuben, D, Greendale, G., & Moore, A. (2009). Light to moderate alcohol consumption and disability: Variable benefits by health status. American Journal of Epidemiology, 169(1), 96-104.

Merkin, S.S., Basurto-Davila, R., Karlamangla, A., Bird, C.E., Lurie, N., Escarce, J., & Seeman, T. (2009). Neighborhoods and cumulative biological risk profiles by race/ethnicity in a national sample of U.S. adults: NHANES III. Annals of Epidemiology, 19(3), 194-201.

Zisman, D.A., Kawut, S.M., Lederer, D.J., Belperio, J.A., Lynch, J.P., Schwartz, M.I., Tayek, J.A., Reuben, D.D., & Karlamangla, A.S. (2008). Serum albumin concentration & waiting list mortality in idiopathic interstitial pneumonia. Chest , 135(4), 929-935.

Seeman, T., Merkin, S.S., Crimmins, E., Koretz, B., Charette, S., & Karlamangla, A. (2008). Education, income and ethnic differences in cumulative biological risk profiles in a national sample of US adults: NHANES III (1988-1994). Social Science and Medicine, 66(1), 72-87.

Chodosh, J., Kado, D., Seeman, T., & Karlamangla, A. (2007). Depressive symptoms as a predictor of cognitive decline: MacArthur Studies of Successful Aging. Journal of the American Geriatrics Society, 15(5), 406-15.

Karlamangla, A.S., Singer, B., & Seeman, T.E. (2006). Reduction in allostatic load is associated with lower all-cause mortality risk in older adults. Psychosomatic Medicine, 68, 500-507.

Moore, A.A., Giuli, L., Gould, R., Hu, P., Zhou, K., Reuben, D.B., Greendale, G.A., & Karlamangla, A.S. (2006). Alcohol Use, Comorbidity and Mortality. Journal of the American Geriatrics Society, 54, 757-762.

Karlamangla, A.S., Zhou, K., Reuben, D.B., Greendale, G.A., & Moore, A.A. (2006). Longitudinal trajectories of heavy drinking in adults in the United States of America. Addiction, 101(1), 91-99.

Karlamangla, A.S., Singer, B., Williams, D., Schwartz, J., Matthews, K., Kiefe, C., & Seeman, TE. (2005). Impact of socioeconomic status on longitudinal accumulation of cardiovascular risk factors in young adults: The CARDIA Study. Social Science and Medicine, 60, 999-1015.

Karlamangla, A.S., Singer, B., Reuben, D., & Seeman, T. (2004). Increases in serum non-high-density-lipoprotein cholesterol over time may be beneficial in high-functioning elderly men and women: MacArthur Studies of Successful Aging. Journal of the American Geriatrics Society, 52(4), 487-494.

Karlamangla, A.S., Young, J., Barrett-Connor, E., & Greendale, G.A. (2004). Hip fracture risk assessment using composite indices of femoral neck strength: The Rancho Bernardo Study. Osteoporosis International, 15(1), 62-70.

Karlamangla, A.S., Singer, B.H., McEwen, B.S., Rowe, J.W., Seeman, T.E. (2002). Allostatic load as a predictor of functional decline: MacArthur Studies of Successful Aging. Journal of Clinical Epidemiology, 55(7), 696-710.
©2011 University of Wisconsin - Madison, Institute on Aging